Registered Nurse Salary in South Carolina

Median pay for Registered Nurses in South Carolina, compared with the national median.

Salary at a glance

High confidence · sourced

Median annual salary for Registered Nurse

$82,360

Mean annual

$87,670

Median hourly

$40

Typical range

$77,320 – $97,230

25th–75th percentile

Employed in US

49,750

Estimate

Reference year

2025

BLS OEWS — May 2025

Based on BLS OEWS — May 2025 data.Wages are estimates; actual pay varies by employer, experience and location.

The national median for Registered Nurses is $97,550. That's $15,190 below the national median.

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